From mountain peaks to stunning coastlines and tropical rainforests teeming with exotic wildlife, and with modern and cosmopolitan cities like Buenos Aires and Rio de Janeiro. On a cruise to South America, you'll be offered a rich and varied selection of experiences and cultures to explore.
South America Cruises
South America is one of the most magical regions in the world. On a cruise, you'll explore thousands of years of history and culture, as well as take in some beautiful scenery along the way.
Popular South American countries to cruise to
Popular cruise lines for South America cruises
South America cruise deals
Browse all our amazing South America America cruise deals below. Use the filters to narrow down the results to find the perfect cruise for you.
South America
We found
3 cruise packages and 206 cruises
1 / 27
7 % off — 5 days left
Duration
4 nights
Date
12 Nov 2026
Ship
MSC Divina
- Departure - Salvador de Bahia, Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Save 40% off your upgrade to All-Inclusive from just £28pp per night!
1 / 27
7 % off — 5 days left
Duration
1 night
Date
15 Nov 2026
Ship
MSC Divina
- Departure - Rio de Janeiro, Brazil
- 2 stops
- Arrival - Santos (São Paulo), Brazil
Available promotion:
Save 40% off your upgrade to All-Inclusive from just £31pp per night!
1 / 19
7 % off — 5 days left
Duration
4 nights
Date
16 Nov 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 4 stops
- Arrival - Santos (São Paulo), Brazil
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Save 40% off your upgrade to All-Inclusive from just £28pp per night!
1 / 26
Duration
4 nights
Date
19 Nov 2026
Ship
Costa Diadema
- Departure - Maceió, Brazil
- 4 stops
- Arrival - Santos (São Paulo), Brazil
Available promotion:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!
1 / 23
Discount — 5 days left
Duration
33 nights
Date
19 Nov 2026
Ship
Majestic Princess
- Departure - Fort Lauderdale, Florida
- 18 stops
- Arrival - Valparaiso, Chile
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Upgrade to Princess Plus from just £53pp per day!
1 / 26
Duration
3 nights
Date
20 Nov 2026
Ship
Costa Diadema
- Departure - Salvador de Bahia, Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
Available promotion:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!
1 / 19
7 % off — 5 days left
Duration
3 nights
Date
23 Nov 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (3)
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Save 40% off your upgrade to All-Inclusive from just £31pp per night!
1 / 19
7 % off — 5 days left
Duration
4 nights
Date
26 Nov 2026
Ship
MSC Musica
- Departure - Santos (São Paulo), Brazil
- 4 stops
- Arrival - Santos (São Paulo), Brazil
Show all departures (2)
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Save 40% off your upgrade to All-Inclusive from just £28pp per night!
1 / 39
7 % off — 5 days left
Duration
4 nights
Date
28 Nov 2026
Ship
MSC Virtuosa
- Departure - Salvador de Bahia, Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Save 40% off your upgrade to All-Inclusive from just £28pp per night!
1 / 33
7 % off — 5 days left
Duration
3 nights
Date
29 Nov 2026
Ship
MSC Seaview
- Departure - Santos (São Paulo), Brazil
- 3 stops
- Arrival - Santos (São Paulo), Brazil
2 Available promotions:
Ends 03/11: Enter code TRICK or TREAT for a mystery discount off your booking!, Save 40% off your upgrade to All-Inclusive from just £31pp per night!
10 of 206 pcs